Piracetam
N06B - Psychostimulants, agents used for ADHD and nootropics
ATC N06BX03
Small molecule
Natural product
JFDA label: Norcetam-800mg tablet
Indications
Approved
- Attention Deficit Disorder with Hyperactivity — attention deficit hyperactivity disorder
Off-label
- Anxiety
- Dementia
- Depressive Disorder
- Movement Disorders
- Postpoliomyelitis Syndrome
- Schizophrenia
Pregnancy & Lactation
Chemistry & Properties
| Formula | C6H10N2O2 |
| Molecular weight | 142.16 g/mol |
| IUPAC name | 2-(2-oxopyrrolidin-1-yl)acetamide |
| CAS | 7491-74-9 |
| PubChem CID | 4843 |
| InChIKey | GMZVRMREEHBGGF-UHFFFAOYSA-N |
| logP | -0.91 (XLogP -1.3) |
| Polar surface area | 63.4 Ų |
| H-bond acceptors / donors | 2 / 1 |
| Drug-likeness (QED) | 0.54 |
| Lipinski violations | 0 |
SMILES
NC(=O)CN1CCCC1=O
Biology & Pharmacokinetics
Pharmacokinetics
Enzyme interactions
| Enzyme | Role | Detail |
| CYP2C19 | Substrate |
— |
Transporters
BCRP (Inhibitor)BSEP (Inhibitor)BSEP (Inhibitor)MRP1 (Inhibitor)MRP3 (Inhibitor)MRP4 (Inhibitor)OATP1B1 (Inhibitor)OATP1B1 (Inhibitor)OATP1B3 (Inhibitor)P-gp (Inhibitor)P-gp (Substrate)
Registered Products (9)
| Brand | Form / strength | Pack | Agent | Citizen (JOD) |
| Norcetam-
|
Capsule 400 mg |
30 cap pack varies |
AL-RAM PHARMA.INDUS.CO.LTD/JORDAN |
2.830 |
| Norcetam-
|
Syrup 200 mg/ml |
120 ml |
AL-RAM PHARMA.INDUS.CO.LTD/JORDAN |
2.930 |
| Memotal Inj
|
Injection 1 g/5 ml |
10 vial |
Nairoukh Drug Store |
3.630 |
| Norcetam-800mg tablet
|
Tablet 800 mg |
30 tab |
AL-RAM PHARMA.INDUS.CO.LTD/JORDAN |
4.540 |
| Nootropil Drinkable Solution
|
Solution 200 mg/ml |
200 ml |
Suleiman Tannous & Sons Co. Ltd |
5.140 |
| Nootropil Ampoules
|
Ampoule 1 g/5 ml |
5 ml |
Suleiman Tannous & Sons Co. Ltd |
6.450 |
| Norcetam-
|
Capsule 400 mg |
500 cap pack varies |
AL-RAM PHARMA.INDUS.CO.LTD/JORDAN |
42.450 |
| Norcetam-
|
Capsule 400 mg |
1000 cap pack varies |
AL-RAM PHARMA.INDUS.CO.LTD/JORDAN |
80.000 |
| Nootropil Infusion
|
Infusion 12 g/60 ml |
60 ml |
Suleiman Tannous & Sons Co. Ltd |
— |