New Release: Alpha testing version has been released.

Piracetam

N06B - Psychostimulants, agents used for ADHD and nootropics ATC N06BX03 Small molecule Natural product

JFDA label: Norcetam-800mg tablet

Indications

Approved

  • Attention Deficit Disorder with Hyperactivity — attention deficit hyperactivity disorder

Off-label

  • Anxiety
  • Dementia
  • Depressive Disorder
  • Movement Disorders
  • Postpoliomyelitis Syndrome
  • Schizophrenia

Pregnancy & Lactation

Pregnancy

Chemistry & Properties

2D structure
FormulaC6H10N2O2
Molecular weight142.16 g/mol
IUPAC name2-(2-oxopyrrolidin-1-yl)acetamide
CAS7491-74-9
PubChem CID4843
InChIKeyGMZVRMREEHBGGF-UHFFFAOYSA-N
logP-0.91 (XLogP -1.3)
Polar surface area63.4 Ų
H-bond acceptors / donors2 / 1
Drug-likeness (QED)0.54
Lipinski violations0
SMILESNC(=O)CN1CCCC1=O

Biology & Pharmacokinetics

Pharmacokinetics

BBB penetrantYes

Enzyme interactions

EnzymeRoleDetail
CYP2C19Substrate

Transporters

BCRP (Inhibitor)BSEP (Inhibitor)BSEP (Inhibitor)MRP1 (Inhibitor)MRP3 (Inhibitor)MRP4 (Inhibitor)OATP1B1 (Inhibitor)OATP1B1 (Inhibitor)OATP1B3 (Inhibitor)P-gp (Inhibitor)P-gp (Substrate)

Registered Products (9)

BrandForm / strengthPackAgentCitizen (JOD)
Norcetam- Capsule 400 mg 30 cap pack varies AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 2.830
Norcetam- Syrup 200 mg/ml 120 ml AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 2.930
Memotal Inj Injection 1 g/5 ml 10 vial Nairoukh Drug Store 3.630
Norcetam-800mg tablet Tablet 800 mg 30 tab AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 4.540
Nootropil Drinkable Solution Solution 200 mg/ml 200 ml Suleiman Tannous & Sons Co. Ltd 5.140
Nootropil Ampoules Ampoule 1 g/5 ml 5 ml Suleiman Tannous & Sons Co. Ltd 6.450
Norcetam- Capsule 400 mg 500 cap pack varies AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 42.450
Norcetam- Capsule 400 mg 1000 cap pack varies AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 80.000
Nootropil Infusion Infusion 12 g/60 ml 60 ml Suleiman Tannous & Sons Co. Ltd