Prifinium

JFDA label: Riabal 7.5mg / 5ml Syrup

Pregnancy & Lactation

Chemistry & Properties

Formula	C22H28N+
Molecular weight	306.47 g/mol
IUPAC name	3-benzhydrylidene-1,1-diethyl-2-methylpyrrolidin-1-ium
CAS	10236-81-4
PubChem CID	4905
InChIKey	ZYEPZINLLPPBMI-UHFFFAOYSA-N
logP	5.14 (XLogP 5.1)
Polar surface area	0.0 Ų
H-bond acceptors / donors	0 / 0
Drug-likeness (QED)	0.69
Lipinski violations	1

SMILES

CC[N+]1(CC)CCC(=C(c2ccccc2)c2ccccc2)C1C

Biology & Pharmacokinetics

Pharmacokinetics

BBB penetrant	No

Enzyme interactions

Enzyme	Role	Detail
CYP1A2	Substrate	—
CYP2B6	Inhibitor	—
CYP2C19	Substrate	—
CYP2C8	Inhibitor	—
CYP2D6	Inhibitor	—

Transporters

BCRP (Inhibitor)BSEP (Inhibitor)MRP1 (Inhibitor)OATP1B1 (Inhibitor)OATP1B3 (Inhibitor)P-gp (Inhibitor)P-gp (Substrate)

Registered Products (14)

Brand	Form / strength	Pack	Agent	Citizen (JOD)
joswe Xpasm Syrup	Syrup 7.5 mg/5 ml	60 ml	Jordan Sweden Medical & Sterilization Co.	0.600
Riabal 7.5mg /	Syrup 7.5 mg/5 ml	60 ml	Hikma Pharmaceuticals Co.Ltd/Jordan	0.750
Riabal Injection	Injection 7.5 mg/ml	6 vial pack varies	Hikma Pharmaceuticals Co.Ltd/Jordan	1.380
Riabal Injection	Injection 7.5 mg/ml	2 ml pack varies	Hikma Pharmaceuticals Co.Ltd/Jordan	1.380
Riabal 30 Tablets	Tablet 30 mg	20 tab pack varies	Hikma Pharmaceuticals Co.Ltd/Jordan	1.610
Riabal Injection	Injection 7.5 mg/ml	6 vial pack varies	Hikma Pharmaceuticals Co.Ltd/Jordan	1.660
Riabal Compound Tablets	Tablet 325 mg, 30 mg	20 tab pack varies	Hikma Pharmaceuticals Co.Ltd/Jordan	1.750
Riabal Injection	Injection 7.5 mg/ml	2 ml pack varies	Hikma Pharmaceuticals Co.Ltd/Jordan	2.620
Riabal Injection	Injection 7.5 mg/ml	2 ml pack varies	Hikma Pharmaceuticals Co.Ltd/Jordan	6.270
Riabal Injection	Injection 7.5 mg/ml	100 vial pack varies	Hikma Pharmaceuticals Co.Ltd/Jordan	12.320
Riabal Injection	Injection 7.5 mg/ml	100 vial pack varies	Hikma Pharmaceuticals Co.Ltd/Jordan	17.400
Riabal Injection	Injection 7.5 mg/ml	120 vial pack varies	Hikma Pharmaceuticals Co.Ltd/Jordan	20.160
Riabal Compound Tablets	Tablet 325 mg, 30 mg	500 tab pack varies	Hikma Pharmaceuticals Co.Ltd/Jordan	25.010
Riabal 30 Tablets	Tablet 30 mg	1000 tab pack varies	Hikma Pharmaceuticals Co.Ltd/Jordan	31.540