New Release: Alpha testing version has been released.

paracetamol

N02B - Other analgesics and antipyretics ATC N02BE01 Small molecule approved 1968 Oral Parenteral Topical Black-box warning

JFDA label: Muscadol Tab

⚠ Black-Box Warning
  • Risk of medication errors and hepatotoxicity (injection):

Mechanism of Action

Inhibitor of Cyclooxygenase — Cyclooxygenase inhibitor; Inhibitor of Fatty-acid amide hydrolase 1 — Anandamide amidohydrolase inhibitor; Opener of Transient receptor potential cation channel subfamily V member 1 — Vanilloid receptor opener

TargetActionGene / class
Cyclooxygenase efficacy INHIBITOR
Fatty-acid amide hydrolase 1 efficacy INHIBITOR FAAH
Transient receptor potential cation channel subfamily V member 1 efficacy OPENER TRPV1

Indications

Approved

  • Fever
  • Injection
  • Oral, Rectal
  • Pain

Contraindications

Source: Lexicomp

  • Injection: Hypersensitivity to acetaminophen or any component of the formulation Absolute
  • severe hepatic impairment or severe active liver disease OTC labeling: When used for self-medication, do not use with other drug products containing acetaminophen or if allergic to acetaminophen or any of the inactive ingredients Absolute

Adverse Reactions

Very Common >10%Common 1–10%Uncommon 0.1–1% Rare 0.01–0.1%Very Rare <0.01%Not Known

Cardiac disorders (4)

Common Hypertension · hypotension · peripheral edema · tachycardia

Nervous system disorders (6)

Common agitation · anxiety · fatigue · Headache · insomnia · trismus

Hepatobiliary disorders (3)

Common Increased serum transaminases

Not Known Increased serum alkaline phosphatase · increased serum bilirubin

Renal and urinary disorders (4)

Common Oliguria

Not Known Hyperammonemia · Nephrotoxicity (with chronic overdose) · renal disease (analgesic)

Blood and lymphatic system disorders (4)

Not Known Anemia · leukopenia · neutropenia · pancytopenia

Immune system disorders (1)

Not Known Hypersensitivity reaction (rare)

Metabolism and nutrition disorders (11)

Common hypervolemia · Hypoalbuminemia · hypokalemia · hypomagnesemia · hypophosphatemia

Not Known Decreased serum bicarbonate · decreased serum calcium · decreased serum sodium · hyperchloremia · hyperuricemia · increased serum glucose

Gastrointestinal disorders (3)

Common abdominal pain · Constipation · diarrhea

Skin and subcutaneous tissue disorders (2)

Common Pruritus

Not Known Skin rash

Musculoskeletal and connective tissue disorders (2)

Common Limb pain · muscle spasm

Eye disorders (1)

Common Periorbital edema

General disorders and administration site conditions (2)

Common Fever · Pain at injection site

Other (3)

Very Common Gastrointestinal: Nausea · vomiting

Not Known Frequency not defined:

Respiratory, thoracic and mediastinal disorders (8)

Common Abnormal breath sounds · atelectasis · dyspnea · hypoxia · pleural effusion · pulmonary edema · stridor · wheezing

Dosing

Source: Lexicomp

Note: In 2011, McNeil Consumer Healthcare reduced the maximum doses and increased the dosing interval on the labeling of some of their acetaminophen OTC products used in older pediatric patients (usually children ≥ 12 years and adolescents) and adults in an attempt to protect consumers from inadvertent overdoses. For example, the maximum daily dose of Tylenol Extra Strength and Tylenol Regular Strength was decreased and the dosing interval for Tylenol Extra Strength was increased. Health care professionals may still prescribe or recommend the 4 g daily maximum to patients (but are advised to use their own discretion and clinical judgment) (McNeil Consumer Healthcare, 2014). Pain or fever: Oral: Note: OTC dosing recommendations may vary by product and/or manufacturer. When calculating the maximum daily dose, consider all sources of acetaminophen (prescription and OTC) and all routes of administration. Do not exceed the maximum recommended daily dose. No dose adjustment required when converting between different acetaminophen formulations. Immediate-release: Regular strength: 650 mg every 4 to 6 hours; maximum daily dose: 3250 mg daily unless directed by health care provider; under health care provider supervision, daily doses ≤4 g may be used Extra strength: 1000 mg every 6 hours; maximum daily dose: 3000 mg daily unless directed by a health care provider; under health care provider supervision, daily doses ≤4 g may be used Extended-release: 1300 mg every 8 hours; maximum daily dose: 3900 mg daily Rectal: 650 mg every 4 to 6 hours; maximum daily dose: 3900 mg daily IV: ≥50 kg: 650 mg every 4 hours or 1,000 mg every 6 hours; maximum single dose: 1,000 mg/dose; maximum daily dose: 4 g/day
(For additional information see "Acetaminophen (paracetamol): Pediatric drug information") Note: In 2011, McNeil Consumer Healthcare reduced the maximum doses and increased the dosing interval on the labeling of some of their acetaminophen OTC products used in older pediatric patients (usually children ≥12 years and adolescents) in an attempt to protect consumers from inadvertent overdoses. For example, the maximum daily dose of Tylenol Extra Strength OTC and Tylenol Regular Strength OTC was decreased and the dosing interval for Tylenol Extra Strength OTC was increased. Health care professionals may still prescribe or recommend the 4 g daily maximum to patients (but are advised to use their own discretion and clinical judgment) (McNeil Consumer Healthcare, 2014). Pain or fever: Oral: Note: When calculating the maximum daily dose, consider all sources of acetaminophen (prescription and OTC) and all routes of administration. Do not exceed the maximum recommended daily dose (see dosing information for further detail). Weight-based dosing: Infants, Children, and Adolescents: 10 to 15 mg/kg/dose every 4 to 6 hours as needed (APS, 2008; Sullivan, 2011); do not exceed 5 doses in 24 hours; maximum daily dose: 75 mg/kg/day not to exceed 4 g daily. Fixed dosing: Oral suspension, chewable tablets: Infants and Children Acetaminophen Pediatric Dosing (Oral)1 Weight (kg) Weight (lbs) Age Dosage (mg) 1Manufacturer’s recommendations are based on weight in pounds (OTC labeling); weight in kg listed here is derived from pounds and rounded; kg weight listed also is adjusted to allow for continuous weight ranges in kg. OTC labeling instructs consumer to consult with health care provider for dosing instructions in infants and children under 2 years of age. 2.7-5.3 6-11 0-3 mo 40 5.4-8.1 12-17 4-11 mo 80 8.2-10.8 18-23 1-2 y 120 10.9-16.3 24-35 2-3 y 160 16.4-21.7 36-47 4-5 y 240 21.8-27.2 48-59 6-8 y 320 27.3-32.6 60-71 9-10 y 400 32.7-43.2 72-95 11 y 480 Immediate release solid dosage formulations: Note: Actual OTC dosing recommendations may vary by product and/or manufacturer: Children 6 to 11 years: 325 mg every 4 to 6 hours; maximum daily dose: 1625 mg daily; Note: Do not use for more than 5 days unless directed by a health care provider Children ≥12 years and Adolescents: Refer to adult dosing. Extended release: Children ≥12 years and Adolescents: Refer to adult dosing. Rectal: Infants 6 to 11 months: 80 mg every 6 hours; maximum daily dose: 320 mg daily Infants and Children 12 to 36 months: 80 mg every 4 to 6 hours; maximum daily dose: 400 mg daily Children >3 to 6 years: 120 mg every 4 to 6 hours; maximum daily dose: 600 mg daily Children >6 up to 12 years: 325 mg every 4 to 6 hours; maximum daily dose: 1625 mg daily Children ≥12 years and Adolescents: Refer to adult dosing. IV: Neonates (including premature neonates born ≥32 weeks gestational age) up to 28 days (fever only): 12.5 mg/kg every 6 hours; maximum daily dose: 50 mg/kg/day. Infants 29 days to 2 year
Pain (acute) or fever: Oral, IV: Refer to adult dosing. Persistent pain (off-label): Adults ≥75 years: Oral: Initial: 325 to 500 mg every 4 hours or 500 to 1,000 mg every 6 hours Maximum: ≤4,000 mg/day. In older adults with hepatic impairment or history of alcohol abuse being treated for persistent pain, do not exceed a maximum of 2,000 to 3,000 mg/day (AGS 2009)
Oral (Aronoff 2007): Adults: GFR ≥50 mL/minute: No dosage adjustment necessary. GFR 10 to 50 mL/minute: Administer every 6 hours. GFR CRRT: Administer every 6 hours. Infants, Children, and Adolescents: GFR ≥10 mL/minute/1.73 m2: No dosage adjustment necessary. GFR 2: Administer every 8 hours. Intermittent hemodialysis or peritoneal dialysis: Administer every 8 hours. CRRT: No dosage adjustment necessary. IV: Children, Adolescents, and Adults: CrCl >30 mL/minute: There are no dosage adjustments provided in the manufacturer's labeling. CrCl ≤30 mL/minute: There are no dosage adjustments provided in the manufacturer's labeling. Use with caution; consider decreasing daily dose and extending dosing interval.
Oral: Use with extreme caution. Although limited data exist, low-dose (≤2 to 3 g/day) therapy is usually well tolerated in hepatic disease/cirrhosis; however, factors such as alcohol use, nutritional status, and renal function must also be taken into consideration (Bosilkovska 2012; Chandok 2010; Dwyer 2014; Hayward 2015, Imani 2014). In patients with hepatic impairment/cirrhosis and active alcohol use, most experts recommend avoiding use as much as possible, and if used, limiting therapy to short-term use only at doses ≤2 g/day (Bosilkovska 2012; Chandok 2010). IV: Mild to moderate impairment: There are no dosage adjustments provided in the manufacturer's labeling. Use with caution; a reduced total daily dosage may be warranted. Severe impairment: Use is contraindicated.

Warnings & Precautions

Source: Lexicomp

Hepatotoxicity

Injection: [US Boxed Warning]. Acetaminophen has been associated with acute liver failure, at times resulting in liver transplant and death. Hepatotoxicity is usually associated with excessive acetaminophen intake and often involves more than one product that contains acetaminophen. Do not exceed the maximum recommended daily dose (>4 g daily in adults). In addition, chronic daily dosing may also result in liver damage in some patients.

Hypersensitivity/anaphylactic reactions

Hypersensitivity and anaphylactic reactions have been reported; discontinue immediately if symptoms of allergic or hypersensitivity reactions occur.

Skin reactions

Serious and potentially fatal skin reactions, including acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) have occurred rarely with acetaminophen use. Discontinue therapy at the first appearance of skin rash. Disease-related concerns:

Ethanol use

Use with caution in patients with alcoholic liver disease; consuming ≥3 alcoholic drinks/day may increase the risk of liver damage.

G6PD deficiency

Use with caution in patients with known G6PD deficiency.

Hepatic impairment

Use with caution in patients with hepatic impairment or active liver disease; use of the IV formulation is contraindicated in patients with severe hepatic impairment or severe active liver disease.

Hypovolemia

Use the IV formulation with caution in patients with severe hypovolemia (eg, due to dehydration or blood loss).

Malnutrition

Use with caution in patients with chronic malnutrition.

Renal impairment

Use with caution in patients with severe renal impairment; consider dosing adjustments. Dosage form specific issues:

Aspartame

Some products may contain aspartame, which is metabolized to phenylalanine and must be avoided (or used with caution) in patients with phenylketonuria.

Benzyl alcohol and derivatives

Some dosage forms may contain benzyl alcohol and/or sodium benzoate/benzoic acid; benzoic acid (benzoate) is a metabolite of benzyl alcohol; large amounts of benzyl alcohol (≥99 mg/kg/day) have been associated with a potentially fatal toxicity (“gasping syndrome”) in neonates; the “gasping syndrome” consists of metabolic acidosis, respiratory distress, gasping respirations, CNS dysfunction (including convulsions, intracranial hemorrhage), hypotension and cardiovascular collapse (AAP ["Inactive" 1997]; CDC 1982); some data suggests that benzoate displaces bilirubin from protein binding sites (Ahlfors 2001); avoid or use dosage forms containing benzyl alcohol and/or benzyl alcohol derivative with caution in neonates. See manufacturer’s labeling.

Injection

Take care to avoid dosing errors; ensure that the dose in mg is not confused with mL, dosing in patients

Polysorbate 80

Some dosage forms may contain polysorbate 80 (also known as Tweens). Hypersensitivity reactions, usually a delayed reaction, have been reported following exposure to pharmaceutical products containing polysorbate 80 in certain individuals (Isaksson, 2002; Lucente 2000; Shelley, 1995). Thrombocytopenia, ascites, pulmonary deterioration, and renal and hepatic failure have been reported in premature neonates after receiving parenteral products containing polysorbate 80 (Alade, 1986; CDC, 1984). See manufacturer’s labeling.

Propylene glycol

Some dosage forms may contain propylene glycol; large amounts are potentially toxic and have been associated hyperosmolality, lactic acidosis, seizures and respiratory depression; use caution (AAP ["Inactive" 1997]; Zar, 2007). Other warnings/precautions:

Dosage limit

Limit acetaminophen dose from all sources (prescription, OTC, combination products) and all routes of administration (IV, oral, rectal) to • Self-medication (OTC use): When used for self-medication, patients should be instructed to contact health care provider if symptoms get worse or new symptoms appear, redness or swelling is present in the painful area, fever lasts >3 days (all ages), or pain (excluding sore throat) lasts longer than: Adults: 10 days, Children and Adolescents: 5 days, Infants: 3 days. When treating children with sore throat, if sore throat is severe, persists for >2 days, or is followed by fever, rash, headache, nausea, or vomiting, consult health care provider immediately.

Pregnancy & Lactation

Pregnancy

FDA category B

Safe

First-line analgesic/antipyretic in pregnancy. Use lowest effective dose for shortest duration. Avoid regular long-term use

Lactation

RID 3.98%

Acetaminophen is excreted in breast milk (Notarianni 1987). The relative infant dose (RID) of acetaminophen is 3.98% when calculated using the highest breast milk concentration located and compared to an infant therapeutic dose of 60 mg/kg/day. In general, breastfeeding is considered acceptable when the RID is 25% breastfeeding should generally be avoided (Anderson 2016; Ito 2000). Using the highest milk concentration (15.9 mcg/mL), the estimated daily infant dose via breast milk is 2.385 mg/k

Monitoring

Clinical pearlSerum acetaminophen levels: Where acute overdose suspected and with long-term use in patients with hepatic disease; relief of pain or fever

Chemistry & Properties

2D structure
FormulaC8H9NO2
Molecular weight151.16 g/mol
IUPAC nameN-(4-hydroxyphenyl)acetamide
CAS103-90-2
PubChem CID1983
InChIKeyRZVAJINKPMORJF-UHFFFAOYSA-N
logP1.35 (XLogP 0.5)
Polar surface area49.33 Ų
H-bond acceptors / donors2 / 2
Drug-likeness (QED)0.60
Lipinski violations0
SMILESCC(=O)Nc1ccc(O)cc1

Biology & Pharmacokinetics

Pharmacokinetics

BBB penetrantYes (logBB -0.3)

Enzyme interactions

EnzymeRoleDetail
CYP2C19Substrate
CYP2D6Substrate
CYP3A4Substrate

Receptor binding (top 1)

TargetActionAffinity
TRPV4 (TRPV4) Inhibitor pIC50 6.5

Transporters

BCRP (Inhibitor)BCRP (Inhibitor)BSEP (Inhibitor)BSEP (Inhibitor)MCT1 (Inhibitor)MDR1 (Inhibitor)MRP1 (Inhibitor)MRP2 (Inhibitor)MRP3 (Inhibitor)MRP4 (Inhibitor)OAT1 (Inhibitor)OAT2 (Inhibitor)OAT3 (Inhibitor)OAT4 (Inhibitor)OATP1B1 (Inhibitor)OATP1B1 (Inhibitor)OATP1B3 (Inhibitor)OATP1B3 (Inhibitor)OATP2B1 (Inhibitor)OCT1 (Inhibitor)OCT2 (Inhibitor)P-gp (Inhibitor)BCRP (Substrate)MDR1 (Substrate)P-gp (Substrate)

Drug–drug interactions (100+, DDInter)

Interacting drugSeverityManagement
Esketamine major
Ethanol major
Leflunomide major
Nitrous acid major
Teriflunomide major
Tizanidine major
Abametapir (topical) moderate
Activated charcoal moderate
Adenosine moderate
Alosetron moderate
Anagrelide moderate
Apalutamide moderate
Asparaginase Escherichia coli moderate
Bendamustine moderate
Benzocaine (topical) moderate
Brentuximab vedotin moderate
Busulfan moderate
Capmatinib moderate
Ceritinib moderate
Cinchocaine (topical) moderate
Ciprofloxacin moderate
Clofarabine moderate
Cocaine (nasal) moderate
Cocaine (topical) moderate
Cycloserine moderate
Dapsone moderate
Dapsone (topical) moderate
Deferasirox moderate
Dicoumarol moderate
Dipyridamole moderate
Duloxetine moderate
Echinacea moderate
Enoxacin moderate
Epirubicin moderate
Fluvoxamine moderate
Givosiran moderate
Glycerol phenylbutyrate moderate
Grepafloxacin moderate
Idelalisib moderate
Imatinib moderate

Showing 40 of 100+.

Registered Products (204)

BrandForm / strengthPackAgentCitizen (JOD)
PAMOL TAB. Tablet 500 mg 20 tab pack varies Dar Al Dawa Development and Investment Co Ltd/Jordan 0.300
Remedol Tablet Tablet 500 mg 20 tab pack varies Al Saleem Drug Store 0.300
Antamol Tablet 125 mg 5 tab pack varies JORDAN RIVER PHARMA.IND(JORIVER)/JORDAN 0.350
PAMOL INFANT SUPP. Suppository 120 mg 5 supp Dar Al Dawa Development and Investment Co Ltd/Jordan 0.350
Revanin Infant Suppositories Suppository 125 mg 5 pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 0.350
Antamol Tablet 250 mg 5 tab pack varies JORDAN RIVER PHARMA.IND(JORIVER)/JORDAN 0.380
Midrone tablet Tablet 500 mg 20 tab pack varies MIDDLE EAST PHARMA&CHEMICAL IND/JORDAN 0.380
PAMOL CHILD SUPP. Suppository 250 mg 5 supp Dar Al Dawa Development and Investment Co Ltd/Jordan 0.380
Revanin Child Supp Suppository 250 mg 5 pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 0.380
Revanin Suspension Suspension 125 mg/5 ml 60 ml pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 0.380
Revanin Tablets Tablet 500 mg 2x10's pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 0.390
Panda Syrup Syrup 125 mg/5 ml 60 ml pack varies Jordan Sweden Medical & Sterilization Co. 0.400
Adol Caplet Tablet 500 mg 24 tab pack varies Professional Drug Store 0.450
PAMOL TAB. Tablet 500 mg 30 tab pack varies Dar Al Dawa Development and Investment Co Ltd/Jordan 0.450
Panda Strong Tablet 1000 mg 12 tab pack varies JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 0.450
Panda Extra Tab Tablet 500 mg, 65 mg 12 tab pack varies Jordan Sweden Medical & Sterilization Co. 0.460
Panda Advance tab Tablet 500 mg 10 tab pack varies Jordan Sweden Medical & Sterilization Co. 0.470
Panda Tablet Tablet 500 mg 24 tab pack varies JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 0.470
Dolocet -500mg tablets Tablet 500 mg 30 tab pack varies AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 0.480
4-All tablet Tablet 80 mg 20 tab Advanced Pharmaceutical Industry 0.500
Paradol Suppository 125 mg 6 SUP/1 BOX pack varies Al-Gadeed Pharmaceutical Industries/JORDAN 0.510
REMEDOL SUSPENSION Suspension 120 mg/5 ml 100 ml JAWEDA INT. DRUD STORE 0.550
Antamol syrup Syrup 125 mg/5 ml 100 ml JORDAN RIVER PHARMA.IND(JORIVER)/JORDAN 0.570
Dolomol Caplet Tablet 500 mg 30 tab Hikma Pharmaceuticals Co.Ltd/Jordan 0.580
Revanin D.S. Suspension Suspension 250 mg/5 ml 60 ml pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 0.580
Revanin Tablets Tablet 500 mg 3x10 pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 0.580
Paradol Suppository 250 mg 6 SUP/1 BOX pack varies Al-Gadeed Pharmaceutical Industries/JORDAN 0.590
4-All tablet Tablet 120 mg 20 tab The Arab Pharmaceutical Manufactruing Co. 0.600
Revanin Suspension Suspension 125 mg/5 ml 100 ml pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 0.640
Omol Oral Drops Oral Drops 100 mg/ml 15 ml Reda Jardaneh Drug Store 0.660
Panda Syrup Syrup 125 mg/5 ml 100 ml pack varies Jordan Sweden Medical & Sterilization Co. 0.660
Panda Tablet Tablet 500 mg 36 tab pack varies JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 0.660
Revanin Infant Suppositories Suppository 125 mg 10 pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 0.670
Revanin Child Supp Suppository 250 mg 10 pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 0.720
Philamol D.S. Suspension Suspension 250 mg/5 ml 100 ml PHILADELPHIA PHAEMACEUTICALS.COMP/JORDAN 0.740
Amaan Susp Suspension 2.4 % 100 ml pack varies JERASH PHARMACEUTICALS LTD.CO/JORDAN 0.750
Newdol Syrup "plus 6 Years" Syrup 160 mg/5 ml 100 MILLILITER Al-Gadeed Pharmaceutical Industries/JORDAN 0.760
Omol Extra Tab Tablet 500 mg, 65 mg 20 tab Reda Jardaneh Drug Store 0.770
Cetamol Advance Tablet 500 mg 24 tab pack varies Hayat Pharmaceutical Industries CO.PLC/JORDAN 0.790
PECTOLYN PEDIATRIC Suspension 125 mg/5 ml, 0.55 mg/5 ml, 7 mg/5 ml, 28.5 mg/ml 150 ml Dar Al Dawa Development and Investment Co Ltd/Jordan 0.790
Cofex syrup Syrup 33.3 mg/5 ml, (as Hcl) 1.65 mg/5 ml, 33.3 mg/5 ml, 33.3 mg/5 ml 100 ml pack varies AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 0.800
Hatso Childrens cough Suspension 100 mg/5 ml, 1 mg/5 ml, 15 mg/5 ml, 5 mg/5 ml 100 ml Pharma International Company/ Jordan 0.800
Hatso Chlidrens Cold Suspension 100 mg/5 ml, 1 mg/5 ml, 15 mg/5 ml 100 ml Pharma International Company/ Jordan 0.800
Revanin Extra Caplets Tablet 500 mg, 65 mg 20 Caplet pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 0.830
Adol Supp. Suppository 125 mg 10 pack varies Professional Drug Store 0.850
Panda Strong Tablet 1000 mg 24 tab pack varies JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 0.850
Paradol Suppository 125 mg 10 supp pack varies Al-Gadeed Pharmaceutical Industries/JORDAN 0.850
Adol Caplet Tablet 500 mg 48 tab pack varies Professional Drug Store 0.870
Panda Extra Tab Tablet 500 mg, 65 mg 24 tab pack varies Jordan Sweden Medical & Sterilization Co. 0.870
Panda-H Syrup Syrup 120 mg/5 ml, 12.5 mg/5 ml 100 ml Jordan Sweden Medical & Sterilization Co. 0.870
bebe Cold Suspension 120 mg/5 ml, 12.5 mg/5 ml 100 ml Al-Gadeed Pharmaceutical Industries 0.870
Trifed PLUS Syrup Syrup 125 mg/5 ml, 1.25 mg/5 ml, 25 mg/5 ml 100 ml Hikma Pharmaceuticals Co.Ltd/Jordan 0.880
Spasmonore comp. Tablet Tablet 250 mg, 10 mg 20 tab THE JORDANIAN PHARMACEUTICAL MANUFACTURING COMPANY/JORDAN 0.890
Amaan Susp Suspension 2.4 % 120 ml pack varies JERASH PHARMACEUTICALS LTD.CO/JORDAN 0.900
Adol Susp. Suspension 250 mg/5 ml 100 ml Professional Drug Store 0.940
Dolocet Extra tablets Tablet 500 mg, 65 mg 30 tab pack varies AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 0.940
Midrone Extra Tablets Tablet 500 mg, 60 mg 30 tab pack varies MIDDLE EAST PHARMA&CHEMICAL IND/JORDAN 0.940
Panda D.S Susp Suspension 250 mg/5 ml 100 ml Jordan Sweden Medical & Sterilization Co. 0.940
SNIP TAB Tablet 325 mg, 1 mg, 15 mg 20 tab pack varies Al Hilal Drug Store 0.940
Cofex syrup Syrup 33.3 mg/5 ml, (as Hcl) 1.65 mg/5 ml, 33.3 mg/5 ml, 33.3 mg/5 ml 120 ml pack varies AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 0.960
Revanin D.S. Suspension Suspension 250 mg/5 ml 100 ml pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 0.960
Rhinostop syrup Syrup 100 mg/5 ml, Maleate 1 mg/5 ml, 20 mg/5 ml 100 ml THE JORDANIAN PHARMACEUTICAL MANUFACTURING COMPANY/JORDAN 0.970
SARIDON TAB Tablet 250 mg, 150 mg, 50 mg 10 tab The Jordan Drugstore Co 0.970
Adol Supp. Suppository 250 mg 10 pack varies Professional Drug Store 0.980
Paradol Suppository 250 mg 10 SUP/1 BOX pack varies Al-Gadeed Pharmaceutical Industries/JORDAN 0.980
Antamol Tablet 125 mg 15 tab pack varies JORDAN RIVER PHARMA.IND(JORIVER)/JORDAN 0.990
Panadol 500 Tab Tablet 500 mg 24 tab pack varies Sukhtian Group 0.990
Muscadol Tab Tablet 450 mg, 35 mg 20 tab pack varies Professional Drug Store 1.000
Revacod Tablets Tablet 500 mg, Phosphate Hemihydrate 10 mg 20 tab pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 1.000
Adol Supp. Suppository 500 mg 10 pack varies Professional Drug Store 1.040
Fludrex Syrup Syrup 120 mg, 0.75 mg/5 ml, 15 mg 120 ml Sun Set Drug Store 1.050
Lemsip Cold & Flu Lemon Tablet 650 mg, 10 mg 5 tab Nairoukh Drug Store 1.050
Antamol Tablet 250 mg 15 tab pack varies JORDAN RIVER PHARMA.IND(JORIVER)/JORDAN 1.070
Rectolyn Suppositories Suppository 66.6 mg, 3.3 mg, 66.6 mg, 66.6 mg 10 Dar Al Dawa Development and Investment Co Ltd/Jordan 1.080
Trifed Plus Tablets Tablet 300 mg, 2.5 mg, 50 mg 20 tab Hikma Pharmaceuticals Co.Ltd/Jordan 1.100
Panda Eff.Tab Effervescent Tablet 500 mg 10 Eff.Tab pack varies Jordan Sweden Medical & Sterilization Co. 1.120
Panadol Advance Tablet 500 mg 24 tab pack varies Sukhtian Group 1.130
Panda Six Plus Suspension 250 mg/5 ml 100 ml pack varies Jordan Sweden Medical & Sterilization Co. 1.130
Cetamol Advance Tablet 500 mg 36 tab pack varies Hayat Pharmaceutical Industries CO.PLC/JORDAN 1.180
Cofex syrup Syrup 33.3 mg/5 ml, (as Hcl) 1.65 mg/5 ml, 33.3 mg/5 ml, 33.3 mg/5 ml 150 ml pack varies AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 1.200
Adol Extra Tablet 500 mg, 65 mg 24 tab Professional Drug Store 1.220
Cetamol Advance Tablet 500 mg 30 tab pack varies Hayat Pharmaceutical Industries CO.PLC/JORDAN 1.220
Adol Supp. Suppository 125 mg 15 pack varies Professional Drug Store 1.230
Savidol Actifast Tablet 500 mg 20 tab Savvy Pharms 1.230
Ascafol Tablet 65 mg, 250 mg, 250 mg 30 tab Advanced Pharmaceutical Industry 1.250
Rhinostop tablet Tablet 250 mg, Maleate 2.5 mg, 60 mg 20 tab pack varies THE JORDANIAN PHARMACEUTICAL MANUFACTURING COMPANY/JORDAN 1.250
taskine pain Tablet 200 mg, 500 mg 30 tab UNITED PHARM.MFG.CO.LTD(UPM)/JORDAN 1.250
Pamol Extra Tablet 65 mg, 500 mg 20 tab Dar Al Dawa Development and Investment Co Ltd/Jordan 1.260
Flutab Sinus 500mg/30mg Tablet 500 mg, 30 mg 20 tab Shawi & Rushedat Drug Store 1.270
Panadol Actifast Tablet 500 mg 20 tab Sukhtian Group 1.290
MYOGESIC TAB. Tablet 450 mg, 35 mg 20 tab pack varies Dar Al Dawa Development and Investment Co Ltd/Jordan 1.300
Pamol Night F.C Tab Film-Coated Tablet 500 mg, 25 mg 20 tab Dar Al Dawa Development and Investment Co Ltd/Jordan 1.300
Panda Extra Tab Tablet 500 mg, 65 mg 36 tab pack varies JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 1.300
Feverol Advance Tablet 500 mg 30 tab pack varies Al-Taqqadom Pharmaceutical Industries 1.340
Feverol Extra 500mg/65mg Tab Tablet 500 mg, 65 mg 30 tab Al-Taqqadom Pharmaceutical Industries 1.340
Panda Advance tab Tablet 500 mg 30 tab pack varies Jordan Sweden Medical & Sterilization Co. 1.340
Panda Eff.Tab Effervescent Tablet 500 mg 12 Eff.Tab pack varies Jordan Sweden Medical & Sterilization Co. 1.340
Pymol Advance Tablet 500 mg 30 tab pack varies Itqan Pharmaceutical Industries 1.340
Pymol Extra Tablet 500 mg, 65 mg 30 tab Itqan Pharmaceutical Industries/Jordan 1.340
Tylenol Extra Strength Tablet 500 mg 24 tab pack varies Al-Amad Drug Store 1.340
Panda Six Plus Suspension 250 mg/5 ml 120 ml pack varies Jordan Sweden Medical & Sterilization Co. 1.360
Remedol Tablet Tablet 500 mg 100 tab pack varies Al Saleem Drug Store 1.360
SNIP TAB Tablet 325 mg, 1 mg, 15 mg 30 tab pack varies Al Hilal Drug Store 1.410
Adol Supp.. Suppository 250 mg 15 pack varies Professional Drug Store 1.420
Midrone Forte Tablets Tablet 250 mg, 150 mg, 50 mg 30 tab pack varies MIDDLE EAST PHARMA&CHEMICAL IND/JORDAN 1.440
Midrone tablet Tablet 500 mg 100 tab pack varies MIDDLE EAST PHARMA&CHEMICAL IND/JORDAN 1.450
Pamol Sinus Tablet 500 mg, 30 mg 20 tab Dar Al Dawa Development and Investment Co Ltd/Jordan 1.450
Revanin Sinus Caplets Tablet 500 mg, 30 mg 20 Caplet The Arab Pharmaceutical Manufactruing Co. 1.450
Adol Supp. Suppository 500 mg 15 pack varies Professional Drug Store 1.500
Dolocet -500mg tablets Tablet 500 mg 100 tab pack varies AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 1.500
Revanin Cold & Flu Caplets Tablet 500 mg, Maleate 2 mg, 30 mg 20 Caplet The Arab Pharmaceutical Manufactruing Co. 1.520
Panda Extra Tab Tablet 500 mg, 65 mg 48 tab pack varies JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 1.550
Panda Night Tablet 500 mg, 25 mg 24 tab JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 1.550
Panda Sinus Double Strength Tablet 1000 mg, 60 mg 12 tab JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 1.550
Tylenol Ultra Relief Tablet 500 mg, 65 mg 20 tab Al-Amad Drug Store 1.580
PanSoft Capsule 500 mg 20 cap Al-motakadema pharmaceutical Ltd/Jordan 1.600
Panda Zokam Tab Tablet 5 mg, 500 mg 20 tab Jordan Sweden Medical & Sterilization Co. 1.600
Panda Strong Tablet 1000 mg 48 tab pack varies JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 1.620
Revanin Night Caplet Tablet 500 mg, 25 mg 20 tab The Arab Pharmaceutical Manufactruing Co. 1.620
Panda Tablet Tablet 500 mg 96 tab pack varies JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 1.700
Adol Caplet Tablet 500 mg 96 tab pack varies Professional Drug Store 1.710
Cetamol sinus Tablet 575.0 mg, 30 mg 20 CAPLET/1 BOX شركة الحياة للصناعات الدوائية / HAYAT PHARMA.INDUSTRIES.CO.LTD/JORDAN / Drug 1.720
IBUMOL-400 Tablet 325 mg, 400 mg 30 tab pack varies Sahar Drug Store 1.730
Panda Migraine Tablet 250 mg, 65 mg, 250 mg 30 tab JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 1.750
Riabal Compound Tablets Tablet 325 mg, 30 mg 20 tab pack varies Hikma Pharmaceuticals Co.Ltd/Jordan 1.750
Revanin Tablets Tablet 500 mg 10x10s pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 1.770
Panda 1000 Effervescent Tablet Effervescent Tablet 1000 mg 10 tab joswe medical 1.840
Bigesic Tablet 325.0 mg, 400.0 mg 30 tab pack varies / JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN / General 1.850
Savidol Joint 665 mg ER F.C Tablet Film-Coated Tablet 665.0 mg 20 tab pack varies SAVVY PHARMA/JORDAN 1.860
Rhinostop tablet Tablet 250 mg, Maleate 2.5 mg, 60 mg 30 tab pack varies THE JORDANIAN PHARMACEUTICAL MANUFACTURING COMPANY/JORDAN 1.880
Panadol Extra With Optizorb (500 mg,65mg) Tablet 500 mg, 65 mg 24 tab pack varies Sukhtian Group 2.100
Lemsip MAX Flu lemon Tablet 1000 mg, 60 mg 10 tab Nairoukh Drug Store 2.110
Lemsip cold & flu lemon Tablet 650 mg, 10 mg 10 tab Nairoukh Drug Store 2.110
Panadol advance Tablet 500 mg 48 tab Sukhtian Group 2.150
Norgesic Tab Tablet 450 mg, 35 mg 48 tab ORIENT DRUG STORE CO 2.170
Panadol Sinus Caplets Tablet 500 mg, 30 mg 24 tab Sukhtian Group 2.170
panadol cold & flu day (500 mg , 5 mg , 25 mg ) Tablet 500 mg, 5 mg, 25 mg 24 Caplet Sukhtian Group 2.280
Panadol Cold & Flu Tablet 500 mg, 2 mg, 30 mg 24 tab Sukhtian Group 2.290
Cetamol Advance Tablet 500 mg 96 tab pack varies Hayat Pharmaceutical Industries CO.PLC/JORDAN 2.400
Panadol Night Tablet 500 mg, 25 mg 24 tab Sukhtian Group 2.590
Panadol Cold and Flu All n one Tablet 250 mg, 5 mg, 100 mg 24 tab Sukhtian Group 2.640
Tylenol Extra Strength Tablet 500 mg 50 tab pack varies Al-Amad Drug Store 2.650
Panadol joint Tablet 665 mg 24 tab Sukhtian Group 2.800
Panadol Advance Tablet 500 mg 72 tab pack varies Sukhtian Group 2.810
Panadol Extra With Optizorb (500 mg,65mg) Tablet 500 mg, 65 mg 48 tab pack varies Sukhtian Group 2.940
Panda Extra Tab Tablet 500 mg, 65 mg 96 tab pack varies JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 2.940
Dolocet Extra Tablets Tablet 500 mg, 65 mg 100 tab pack varies AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 2.950
Relaxon Tablet 300 mg, 250 mg 30 tab شركة مستودع ادوية الايمان 2.970
Panadol 500 Tab Tablet 500 mg 96 tab pack varies Sukhtian Group 3.000
MYOGESIC TAB. Tablet 450 mg, 35 mg 50 tab pack varies Dar Al Dawa Development and Investment Co Ltd/Jordan 3.090
Feverol Advance Tablet 500 mg 100 tab pack varies Al-Taqqadom Pharmaceutical Industries 3.100
Pymol Advance Tablet 500 mg 105 tab pack varies Itqan Pharmaceutical Industries 3.210
Panadol Cold & Flu Vapour Release +Decongestant Sachet 600 mg, 10 mg 10 sachet Sukhtian Group 3.310
Panda Advance tab Tablet 500 mg 100 tab pack varies Jordan Sweden Medical & Sterilization Co. 3.520
Savidol Joint 665 mg ER F.C Tablet Film-Coated Tablet 665.0 mg 40 tab pack varies SAVVY PHARMA/JORDAN 3.530
Panadol Advance Tablet 500 mg 96 tab pack varies Sukhtian Group 3.550
parasustain Tablet 665 mg 48 tab Roya Tholathiyat Al Abaad Drug Store 3.570
Revanin Extra Caplets Tablet 500 mg, 65 mg 100 Caplet pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 3.820
Tylenol Extra Strength Tablet 500 mg 100 tab pack varies Al-Amad Drug Store 3.900
IBUMOL-400 Tablet 325 mg, 400 mg 100 tab pack varies Sahar Drug Store 4.300
PAMOL TAB. Tablet 500 mg 500 tab pack varies Dar Al Dawa Development and Investment Co Ltd/Jordan 4.880
Panadol Migraine Tablet 250 mg, 65 mg, 250 mg 24 Caplets Sukhtian Group 4.970
Panadol Extra With Optizorb (500 mg,65mg) Tablet 500 mg, 65 mg 72 tab pack varies Sukhtian Group 5.730
Revanin Infant Suppositories Suppository 125 mg 100 pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 6.300
Revanin Child Supp Suppository 250 mg 100 pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 6.460
Midrone Extra Tablets Tablet 500 mg, 60 mg 500 tab pack varies MIDDLE EAST PHARMA&CHEMICAL IND/JORDAN 7.250
Adol Supp. Suppository 125 mg 100 pack varies Professional Drug Store 7.670
Bigesic Tablet 325.0 mg, 400.0 mg 200 tab pack varies / JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN / General 11.350
Panda Tablets Tablet 500 mg 960 tab pack varies JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 12.150
Dolocet -500mg tablets Tablet 500 mg 1000 tab pack varies AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 13.600
Antamol Tablet 250 mg 250 tab pack varies JORDAN RIVER PHARMA.IND(JORIVER)/JORDAN 15.200
Muscadol Tab Tablet 450 mg, 35 mg 1000 tab pack varies Professional Drug Store 15.790
Revanin Tablets Tablet 500 mg 1000 tab pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 16.580
MYOGESIC TAB. Tablet 450 mg, 35 mg 500 tab pack varies Dar Al Dawa Development and Investment Co Ltd/Jordan 20.510
Revanin Suspension Suspension 125 mg/5 ml 100 ml pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 23.380
Riabal Compound Tablets Tablet 325 mg, 30 mg 500 tab pack varies Hikma Pharmaceuticals Co.Ltd/Jordan 25.010
Dolocet Extra Tablets Tablet 500 mg, 65 mg 1000 tab pack varies AL-RAM PHARMA.INDUS.CO.LTD/JORDAN 26.630
Midrone Forte Tablets Tablet 250 mg, 150 mg, 50 mg 1000 tab pack varies MIDDLE EAST PHARMA&CHEMICAL IND/JORDAN 26.670
Panda Extra Tab Tablet 500 mg, 65 mg 960 tab pack varies JORDAN SWEDEN MEDICAL&STERILE.CO(JOSWE)/JORDAN 27.840
Pymol Advance Tablet 500 mg 1020 tab pack varies Itqan Pharmaceutical Industries 30.240
Revacod Tablets Tablet 500 mg, Phosphate Hemihydrate 10 mg 1000 tab pack varies The Arab Pharmaceutical Manufacturing PSC/Salt 42.500
Rhinostop tablet Tablet 250 mg, Maleate 2.5 mg, 60 mg 1000 tab pack varies THE JORDANIAN PHARMACEUTICAL MANUFACTURING COMPANY/JORDAN 53.130
Paradol Suppository 125 mg 1000 supp pack varies Al-Gadeed Pharmaceutical Industries/JORDAN 72.250
Adol Supp.. Suppository 250 mg 100 pack varies Professional Drug Store
Apotel max Solution for Infusion 1g/100ml Infusion 1GM/100 ml (12 BAG) Al Hilal Drug Store
Caffate 60mg/3ml Solution for Infusion Infusion 60 mg/ml 10 vial MS PHARMA/JORDAN
Combogesic Vial Sodium Ibuprofen Dihydrate 385.00 mg/100 ml, Acetaminophen 1000.00 mg/100 ml 10 vial Hikma Pharmaceuticals LLC
Dolorgan Infusion 1 g/100 ml 12 PP Bag pack varies Hikma Pharmaceuticals Co.Ltd/Jordan
Dolorgan Infusion 1 g/100 ml 1 PP Bag pack varies Hikma Pharmaceuticals Co.Ltd/Jordan
IFIMOL IV (Paracetamol Solution for Intravenous Infusion 10 mg/ml) Infusion 10 mg/1 ml 1 vial Roya Tholathiyat Al Abaad Drug Store
MakoAche Vial 10 mg/ml 10 vial Adonis Drug Store
PARACEROL Vial 10 mg/ml 12 vial JAWEDA INT. DRUD STORE
Paracetamol Aguettant10mg/ml Solution for Infusion (100ml) Infusion 10 mg/ml 100 ml pack varies شركة مستودع ادوية جرينلاند
Paracetamol Aguettant10mg/ml Solution for Infusion (50ml) Infusion 10 mg/ml 50 ml pack varies شركة مستودع ادوية جرينلاند
Paracetamol B.Braun 10mg/ml (100ml) Injection 10 mg/ml 100 ml THE ARAB DRUG STORE P.S.C
Paracetamol Kabi 10 mg/ml solution for infusion Infusion 10.0 mg/1 ml 10 vial Sun Set Drug Store
Paraconica 1000mg IV Vial 10 mg/ml 10 vial Khoury Drug Store
Paradol Suppository 250 mg 1000 SUP/1 BOX pack varies Al-Gadeed Pharmaceutical Industries/JORDAN
Paramed Infusion 1 g/100 ml 100 ml Land Of Medicine Drug Store
Paravin 10mg/1ml Solution For Inj Injection 10 mg/1 ml 1 vial MS PHARMA/JORDAN
Qatar Paracetamol Inj Powder for Injection 1 % 100 ml Petra Drug Store
STOPALGIC Vial 10 mg/1 ml 12 vial Professional Drug Store
Tamin Solution 10 mg/ml 100 ml pack varies Khoury Drug Store
Tamin Solution 10 mg/ml 100 ml pack varies Khoury Drug Store